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104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema

104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema

    • 104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema
    • 104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema
    • 104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema
  • 104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema

    รายละเอียดสินค้า:

    Place of Origin: China
    ชื่อแบรนด์: Sendi
    ได้รับการรับรอง: SGS,ISO9001
    Model Number: 104987-11-3

    การชำระเงิน:

    Minimum Order Quantity: 5 Grams
    ราคา: 1~3 USD
    Packaging Details: discreet and safe foil bag or tin
    Delivery Time: Within 12hours after payment
    Payment Terms: L/C, D/A, T/T, Western Union, MoneyGram,Bitcorn and bank transfer
    Supply Ability: 5000kilogram per month
    ติดต่อตอนนี้
    รายละเอียดสินค้า
    Name: Tacrolimus MF: C44H69NO12
    Purity: 99.0% Min Key Words: Tacrolimus
    Appearance: White Crystalline Solid CAS: 104987-11-3
    Product Categories: Pharmaceuticals;Chiral Reagents;Fujimycin, Prograf;antibiotic Use: Liver Transplantation

    Best Quality Anti-Inflammatory USP34 Tacrolimus 104987-11-3 Use in Liver Transplantation

     

    Quick Details:

     

    Tacrolimus

    CAS: 104987-11-3
    MF: C44H69NO12
    MW: 804.02
    Product Categories:Pharmaceuticals;Chiral Reagents;Fujimycin, Prograf;antibiotic
    Chemical Properties: White Crystalline Solid
    Assay:99%
    Usage: An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
    Packing:2g/foil bag



    Description:

    Tacrolimus is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

     

    Application:

    Heart liver kidney and bone marrow transplant patients preferred immune-suppressing drugs after the transplant rejection resistant to conventional immunosuppressive regimen, is also the choice of the drug... Adverse reactions similar to cyclosporine. autoimmune eye disease and other autoimmune diseases also play an active role.
     


    COA:
     

    Tests Specifications Results
    Description A white or off-white crystalline powder Conform
    Identification 1. IR (USP <197K>) Conform
      2. HPLC retention times Conform
    Water
    (USP <921> Method I)
    1.6 ~ 3.0% 2.1%
    Residue on ignition
    (USP <281>)
    £ 0.2% 0.08%
    Heavy metals
    (USP <231> II)
    £ 20 ppm < 20 ppm
    Related substances (In-house HPLC method) Ascomycin £ 0.8% 0.064%
    Residual solvents
    (In-house method)
    Acetone £ 2000 ppm Not detected
    Assay (on anhydrous basis) 98.0% ~ 102.0% 100.0%
    Conclusion: Complied with In-House standard

     

     

    Function:

    It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.

    As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.

    It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face

     

     

    More details:

    Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference.

    Payment: Western Union, MoneyGram We will supply the receiver's information or the bank account information for payment use.

    Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received.
    Every item will be shipped out in 1-2working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment.

    We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

     

    104987-11-3 Pharmaceutical Intermediates Generic Tacrolimus Ointment Medicat For Eczema

     

    รายละเอียดการติดต่อ
    Shenzhen Sendi Biotechnology Co.Ltd.

    ผู้ติดต่อ: Demi

    โทร: +8618123940985

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